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The
Nobel Prize in Physiology or Medicine
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诺贝尔医学奖得主文章免费开放下载 |
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爱思唯尔ELSEVIER谨向诺贝尔奖获奖大师们表示崇高的敬意和热烈的祝贺!为答谢荣获诺贝尔奖的科学家们对爱思唯尔的厚爱和贡献,我公司非常荣幸地向读者提供他们在爱思唯尔期刊发表的论文全文。
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历年诺贝尔医学奖得主论文集成 |
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2006年诺贝尔医学奖
他们的发现...
免费阅读Andrew
Z. Fire在ELSEVIER期刊上发表的20篇论文全文
免费阅读Craig
C. Mello 在ELSEVIER期刊上发表的17篇论文全文
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Cyclin D involvement demarcates a late transition
in C. elegans embryogenesis Developmental Biology,
Volume 279, Issue 1, 1 March 2005, Pages 244-251 Judith Yanowitz and
Andrew Fire
PDF (556 K)
Abstract
via ScienceDirect
UNC-39, the C. elegans homolog of the
human myotonic dystrophy-associated homeodomain protein Six5,
regulates cell motility and differentiation
Developmental Biology, Volume 272, Issue 2, 15 August 2004,
Pages 389-402 Judith L. Yanowitz, M. Afaq Shakir, Edward Hedgecock,
Harald Hutter, Andrew Z. Fire and Erik A. Lundquist
PDF (992 K)
Abstract
via ScienceDirect
Loss of the Putative RNA-Directed RNA
Polymerase RRF-3 Makes C. elegans Hypersensitive to RNAi
Current Biology, Volume 12, Issue 15, 6 August 2002, Pages
1317-1319 Femke Simmer, Marcel Tijsterman, Susan Parrish, Sandhya P.
Koushika, Michael L. Nonet, Andrew Fire, Julie Ahringer and
Ronald H. A. Plasterk
PDF (145 K)
Abstract
via ScienceDirect
On the Role of RNA Amplification in
dsRNA-Triggered Gene Silencing Cell, Volume 107,
Issue 4, 16 November 2001, Pages 465-476 Titia Sijen, Jamie Fleenor,
Femke Simmer, Karen L. Thijssen, Susan Parrish, Lisa Timmons, Ronald
H. A. Plasterk and Andrew Fire
PDF (1341 K)
Abstract
via ScienceDirect
Genes and Mechanisms Related to RNA
Interference Regulate Expression of the Small Temporal RNAs that
Control C. elegans Developmental Timing Cell,
Volume 106, Issue 1, 13 July 2001, Pages 23-34 Alla Grishok, Amy E.
Pasquinelli, Darryl Conte, Na Li, Susan Parrish, Ilho Ha, David L.
Baillie, Andrew Fire, Gary Ruvkun and Craig C. Mello
PDF (466 K)
Abstract
via Science Direct
Ingestion of bacterially expressed
dsRNAs can produce specific and potent genetic interference in
Caenorhabditis elegans Gene, Volume 263, Issues
1-2, 24 January 2001, Pages 103-112 Lisa Timmons, Donald L. Court
and Andrew Fire
PDF (728 K)
Abstract
via Science Direct
The MADS-Box Factor CeMEF2 Is Not
Essential for Caenorhabditis elegans Myogenesis and Development
Developmental Biology, Volume 223, Issue 2, 15 July 2000,
Pages 431-440 Daryl Dichoso, Thomas Brodigan, Kyu Yeong Chwoe, Jin
Sook Lee, Reymond Llacer, Morgan Park, Ann K. Corsi, Stephen A.
Kostas, Andrew Fire, Joohong Ahnn and Michael Krause
PDF (291 K)
Abstract
via Science Direct
dsRNA-mediated gene silencing in
cultured Drosophila cells: a tissue culture model for the analysis
of RNA interference Gene, Volume 252, Issues 1-2,
11 July 2000, Pages 95-105 Natasha J. Caplen, Jamie Fleenor,
Andrew Fire and Richard A. Morgan
PDF (443 K)
Abstract
via Science Direct
Functional Anatomy of a dsRNA Trigger:
Differential Requirement for the Two Trigger Strands in RNA
Interference Molecular Cell, Volume 6, Issue 5,
November 2000, Pages 1077-1087 Susan Parrish, Jamie Fleenor, SiQun
Xu, Craig Mello and Andrew Fire
PDF (1239 K)
Abstract
via Science Direct
The rde-1 Gene, RNA Interference, and
Transposon Silencing in C. elegans Cell, Volume
99, Issue 2, 15 October 1999, Pages 123-132 Hiroaki Tabara, Madathia
Sarkissian, William G. Kelly, Jamie Fleenor, Alla Grishok, Lisa
Timmons, Andrew Fire and Craig C. Mello
PDF (264 K)
Abstract
via Science Direct
RNA-triggered gene silencing
Trends in Genetics, Volume 15, Issue 9, 1 September 1999,
Pages 358-363 Andrew Fire
PDF (222 K)
Abstract
via Science Direct
Evolutionary Conservation of MyoD
Function and Differential Utilization of E Proteins
Developmental Biology, Volume 208, Issue 2, 15 April 1999, Pages
465-472 Jian-Min Zhang, Lihsia Chen, Michael Krause, Andrew Fire
and Bruce M. Paterson
PDF (183 K)
Abstract
via Science Direct
Reply Trends in Genetics,
Volume 15, Issue 1, 1 January 1999, Page 12 Andrew Fire and
Mary Montgomery
PDF (74 K)
Abstract
via Science Direct
Double-stranded RNA as a mediator in
sequence-specific genetic silencing and co-suppression
Trends in Genetics, Volume 14, Issue 7, 1 July 1998, Pages
255-258 Mary K. Montgomery and Andrew Fire
PDF (158 K)
Abstract
via Science Direct
Elements Regulating Cell- and
Stage-Specific Expression of the C. elegans MyoD Family Homolog
hlh-1 Developmental Biology, Volume 166, Issue 1,
November 1994, Pages 133-148 Michael Krause, Susan White Harrison,
Si-Qun Xu, Lihsia Chen and Andrew Fire
PDF (1272 K)
Abstract
via Science Direct
Histochemical techniques for locating
Escherichia coli β-galactosidase activity in transgenic organisms
Genetic Analysis: Biomolecular Engineering, Volume 9, Issues
5-6, October-December 1992, Pages 151-158 Andrew Fire
PDF (776 K)
Abstract
via Science Direct
CeMyoD accumulation defines the body
wall muscle cell fate during C. elegans embryogenesis
Cell, Volume 63, Issue 5, 30 November 1990, Pages 907-919
Michael Krause, Andrew Fire, Susan White Harrison, James
Priess and Harold Weintraub
PDF (5901 K)
Abstract
via Science Direct
A modular set of lacZ fusion vectors for
studying gene expression in Caenorhabditis elegans
Gene, Volume 93, Issue 2, 1990, Pages 189-190 Andrew Fire,
Susan White Harrison and Dennis Dixon
PDF (1401 K)
Abstract
via Science Direct
[35] In Vitro transcription: Whole-cell
extract Methods in Enzymology, Volume 101, 1983,
Pages 568-582 James L. Manley, Andrew Fire, Mark Samuels and
Phillip A. Sharp
PDF (934 K)
Abstract
via Science Direct
Inhibition of transcription factor
activity by poliovirus Cell, Volume 27, Issue 3,
Part 2, December 1981, Pages 555-561 Nigel Crawford, Andrew Fire,
Mark Samuels, Phillip A. Sharp and David Baltimore
PDF (2004 K)
Abstract
via Science Direct |
The Conserved Kinases CDK-1, GSK-3, KIN-19, and MBK-2 Promote OMA-1 Destruction to Regulate the Oocyte-to-Embryo Transition in C. elegans Current Biology, Volume 16, Issue 1, 10 January 2006, Pages 47-55 Masaki Shirayama, Martha C. Soto, Takao Ishidate, Soyoung Kim, Kuniaki Nakamura, Yanxia Bei, Sander van den Heuvel and Craig C. Mello
PDF (753 K) Abstract via ScienceDirect
The Conserved Kinases CDK-1, GSK-3, KIN-19, and MBK-2 Promote OMA-1 Destruction to Regulate the Oocyte-to-Embryo Transition in C. elegans Current Biology, Volume 16, Issue 1, 10 January 2006, Page 118 Masaki Shirayama, Martha C. Soto, Takao Ishidate, Soyoung Kim, Kuniaki Nakamura, Yanxia Bei, Sander van den Heuvel and Craig C. Mello
PDF (23 K) Abstract via ScienceDirect
A Member of the Polymerase β Nucleotidyltransferase Superfamily Is Required for RNA Interference in C. elegans Current Biology, Volume 15, Issue 4, 22 February 2005, Pages 378-383 Chun-Chieh G. Chen, Martin J. Simard, Hiroaki Tabara, Daniel R. Brownell, Jennifer A. McCollough and Craig C. Mello
PDF (460 K) Abstract via ScienceDirect
The minibrain kinase homolog, mbk-2, is required for spindle positioning and asymmetric cell division in early C. elegans embryos Developmental Biology, Volume 265, Issue 1, 1 January 2004, Pages 127-139 Ka Ming Pang, Takao Ishidate, Kuniaki Nakamura, Masaki Shirayama, Chris Trzepacz, Charlotte M. Schubert, James R. Priess and Craig C. Mello
PDF (1858 K) Abstract via ScienceDirect
Chromatin regulation during C. elegans germline development Current Opinion in Genetics & Development, Volume 13, Issue 5, October 2003, Pages 455-462 Tae Ho Shin and Craig C Mello
PDF (235 K) Abstract via Science Direct
MEP-1 and a Homolog of the NURD Complex Component Mi-2 Act Together to Maintain Germline-Soma Distinctions in C. elegans Cell, Volume 111, Issue 7, 27 December 2002, Pages 991-1002 Yingdee Unhavaithaya, Tae Ho Shin, Nicholas Miliaras, Jungsoon Lee, Tomoko Oyama and Craig C. Mello
PDF (496 K) Abstract via Science Direct
SRC-1 and Wnt Signaling Act Together to Specify Endoderm and to Control Cleavage Orientation in Early C. elegans Embryos Developmental Cell, Volume 3, Issue 1, July 2002, Pages 113-125 Yanxia Bei, Jennifer Hogan, Laura A. Berkowitz, Martha Soto, Christian E. Rocheleau, Ka Ming Pang, John Collins and Craig C. Mello
PDF (752 K) Abstract via Science Direct
The dsRNA Binding Protein RDE-4 Interacts with RDE-1, DCR-1, and a DExH-Box Helicase to Direct RNAi in C. elegans Cell, Volume 109, Issue 7, 28 June 2002, Pages 861-871 Hiroaki Tabara, Erbay Yigit, Haruhiko Siomi and Craig C. Mello
PDF (453 K) Abstract via Science Direct
11 RNAi (nematodes: Caenorhabditis elegans) Advances in Genetics, Volume 46, 2002, Pages 339-360 Alla Grishok and Craig C. Mello
PDF (4585 K) Abstract via Science Direct
Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing Cell, Volume 106, Issue 1, 13 July 2001, Pages 23-34 Alla Grishok, Amy E. Pasquinelli, Darryl Conte, Na Li, Susan Parrish, Ilho Ha, David L. Baillie, Andrew Fire, Gary Ruvkun and Craig C. Mello
PDF (466 K) Abstract via Science Direct
The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans Cell, Volume 99, Issue 2, 15 October 1999, Pages 123-132 Hiroaki Tabara, Madathia Sarkissian, William G. Kelly, Jamie Fleenor, Alla Grishok, Lisa Timmons, Andrew Fire and Craig C. Mello
PDF (264 K) Abstract via Science Direct
MOM-4, a MAP Kinase Kinase Kinase–Related Protein, Activates WRM-1/LIT-1 Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans Molecular Cell, Volume 4, Issue 2, August 1999, Pages 275-280 Tae Ho Shin, Jun Yasuda, Christian E. Rocheleau, Rueyling Lin, Martha Soto, Yanxia Bei, Roger J. Davis and Craig C. Mello
PDF (157 K) Abstract via Science Direct
WRM-1 Activates the LIT-1 Protein Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans Cell, Volume 97, Issue 6, 11 June 1999, Pages 717-726 Christian E. Rocheleau, Jun Yasuda, Tae Ho Shin, Rueyling Lin, Hitoshi Sawa, Hideyuki Okano, James R. Priess, Roger J. Davis and Craig C. Mello
PDF (363 K) Abstract via Science Direct
Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos Cell, Volume 90, Issue 4, 22 August 1997, Pages 707-716 Christian E. Rocheleau , William D. Downs , Rueyling Lin , Claudia Wittmann , Yanxia Bei , Yoon-Hee Cha , Mussa Ali , James R. Priess and Craig C. Mello
PDF (306 K) Abstract via Science Direct
MEX-3 Is a KH Domain Protein That Regulates Blastomere Identity in Early C. elegans Embryos Cell, Volume 87, Issue 2, 18 October 1996, Pages 205-216 Bruce W. Draper, Craig C. Mello, Bruce Bowerman, Jeff Hardin and James R. Priess
PDF (666 K) Abstract via Science Direct
The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos Cell, Volume 74, Issue 3, 13 August 1993, Pages 443-452 Bruce Bowerman, Bruce W. Draper, Craig C. Mello and James R. Priess
PDF (3421 K) Abstract via Science Direct
The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos Cell, Volume 70, Issue 1, 10 July 1992, Pages 163-176 Craig C. Mello, Bruce W. Draper, Michael Krause, Harold Weintraub and James R. Priess
PDF (1766 K) Abstract via Science Direct |
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